Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGB3BPCentromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. (177 aa)    
Predicted Functional Partners:
CENPU
Centromere protein U.
   
 0.997
CENPQ
Centromere protein Q.
   
 0.997
CENPT
CENPT isoform 2.
    
 0.995
CENPI
Centromere protein I.
    
 0.994
CR201_G0009017
CENPP isoform 1.
    
 0.993
CENPN
Centromere protein N.
   
 0.989
CENPK
Centromere protein K.
   
 0.985
CENPM
Centromere protein M.
    
 0.973
CENPH
Centromere protein H.
   
 0.971
CENPL
CENPL isoform 1.
    
 0.966
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (8%) [HD]