STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK7DOCK7 isoform 6; Belongs to the DOCK family. (2108 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.970
LRCH3
LRCH3 isoform 8.
   
 
 0.954
MYO6
MYO6 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.881
DOCK8
DOCK8 isoform 2; Belongs to the DOCK family.
  
 
 
0.820
LRCH1
LRCH1 isoform 2.
   
 
 0.776
RHOJ
Ras homolog family member J.
   
 0.630
DHX37
DHX37 isoform 2.
      
 0.549
RHOQ
RHOQ isoform 1.
   
 0.548
RAC3
RAC3 isoform 1.
   
 0.539
RAC2
Rac family small GTPase 2.
   
 0.539
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.