| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FANCD2 | FANCI | ENSPPYP00000015279 | ENSPPYP00000007672 | FANCD2 isoform 1. | FANCI isoform 2. | 0.999 |
| FANCD2 | FANCL | ENSPPYP00000015279 | ENSPPYP00000013826 | FANCD2 isoform 1. | FA complementation group L. | 0.999 |
| FANCD2 | PCNA | ENSPPYP00000015279 | ENSPPYP00000012059 | FANCD2 isoform 1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.837 |
| FANCD2 | UBA52 | ENSPPYP00000015279 | ENSPPYP00000010917 | FANCD2 isoform 1. | UBA52 isoform 10. | 0.867 |
| FANCD2 | UBC | ENSPPYP00000015279 | ENSPPYP00000005811 | FANCD2 isoform 1. | UBC isoform 2. | 0.921 |
| FANCD2 | USP1 | ENSPPYP00000015279 | ENSPPYP00000001497 | FANCD2 isoform 1. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.981 |
| FANCD2 | WDR48 | ENSPPYP00000015279 | ENSPPYP00000015661 | FANCD2 isoform 1. | WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes; Belongs to the WD repeat WDR48 family. | 0.866 |
| FANCI | FANCD2 | ENSPPYP00000007672 | ENSPPYP00000015279 | FANCI isoform 2. | FANCD2 isoform 1. | 0.999 |
| FANCI | FANCL | ENSPPYP00000007672 | ENSPPYP00000013826 | FANCI isoform 2. | FA complementation group L. | 0.998 |
| FANCI | PCNA | ENSPPYP00000007672 | ENSPPYP00000012059 | FANCI isoform 2. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.599 |
| FANCI | UBA52 | ENSPPYP00000007672 | ENSPPYP00000010917 | FANCI isoform 2. | UBA52 isoform 10. | 0.864 |
| FANCI | UBC | ENSPPYP00000007672 | ENSPPYP00000005811 | FANCI isoform 2. | UBC isoform 2. | 0.882 |
| FANCI | USP1 | ENSPPYP00000007672 | ENSPPYP00000001497 | FANCI isoform 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.949 |
| FANCI | WDR48 | ENSPPYP00000007672 | ENSPPYP00000015661 | FANCI isoform 2. | WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes; Belongs to the WD repeat WDR48 family. | 0.938 |
| FANCL | FANCD2 | ENSPPYP00000013826 | ENSPPYP00000015279 | FA complementation group L. | FANCD2 isoform 1. | 0.999 |
| FANCL | FANCI | ENSPPYP00000013826 | ENSPPYP00000007672 | FA complementation group L. | FANCI isoform 2. | 0.998 |
| FANCL | PCNA | ENSPPYP00000013826 | ENSPPYP00000012059 | FA complementation group L. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.724 |
| FANCL | UBA52 | ENSPPYP00000013826 | ENSPPYP00000010917 | FA complementation group L. | UBA52 isoform 10. | 0.425 |
| FANCL | UBC | ENSPPYP00000013826 | ENSPPYP00000005811 | FA complementation group L. | UBC isoform 2. | 0.569 |
| FANCL | USP1 | ENSPPYP00000013826 | ENSPPYP00000001497 | FA complementation group L. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.973 |
