ENSPPYP00000001503 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSPPYP00000001503

annotation not available (110 aa)

Predicted Functional Partners:

PTS

0.673

MCEE

0.603

PRKG2

0.577

PAH

0.575

DBH

0.485

PCBD1

0.476

QDPR

0.451

GCHFR

0.442

GCH1

0.434

EXOSC1

0.420

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DBH	ENSPPYP00000001503	ENSPPYP00000022139	ENSPPYP00000001503	DBH isoform 1.	annotation not available	0.485
DBH	PAH	ENSPPYP00000022139	ENSPPYP00000005573	DBH isoform 1.	Phenylalanine hydroxylase.	0.695
ENSPPYP00000001503	DBH	ENSPPYP00000001503	ENSPPYP00000022139	annotation not available	DBH isoform 1.	0.485
ENSPPYP00000001503	EXOSC1	ENSPPYP00000001503	ENSPPYP00000002937	annotation not available	Exosome component 1.	0.420
ENSPPYP00000001503	GCH1	ENSPPYP00000001503	ENSPPYP00000006627	annotation not available	GTP cyclohydrolase 1.	0.434
ENSPPYP00000001503	GCHFR	ENSPPYP00000001503	ENSPPYP00000007200	annotation not available	GTP cyclohydrolase I feedback regulator.	0.442
ENSPPYP00000001503	MCEE	ENSPPYP00000001503	ENSPPYP00000013730	annotation not available	MCEE isoform 2.	0.603
ENSPPYP00000001503	PAH	ENSPPYP00000001503	ENSPPYP00000005573	annotation not available	Phenylalanine hydroxylase.	0.575
ENSPPYP00000001503	PCBD1	ENSPPYP00000001503	ENSPPYP00000002745	annotation not available	Pterin-4 alpha-carbinolamine dehydratase 1.	0.476
ENSPPYP00000001503	PRKG2	ENSPPYP00000001503	ENSPPYP00000016617	annotation not available	cGMP-dependent protein kinase.	0.577
ENSPPYP00000001503	PTS	ENSPPYP00000001503	ENSPPYP00000004445	annotation not available	6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity).	0.673
ENSPPYP00000001503	QDPR	ENSPPYP00000001503	ENSPPYP00000016338	annotation not available	Quinoid dihydropteridine reductase.	0.451
EXOSC1	ENSPPYP00000001503	ENSPPYP00000002937	ENSPPYP00000001503	Exosome component 1.	annotation not available	0.420
GCH1	ENSPPYP00000001503	ENSPPYP00000006627	ENSPPYP00000001503	GTP cyclohydrolase 1.	annotation not available	0.434
GCH1	GCHFR	ENSPPYP00000006627	ENSPPYP00000007200	GTP cyclohydrolase 1.	GTP cyclohydrolase I feedback regulator.	0.986
GCH1	PAH	ENSPPYP00000006627	ENSPPYP00000005573	GTP cyclohydrolase 1.	Phenylalanine hydroxylase.	0.525
GCH1	PCBD1	ENSPPYP00000006627	ENSPPYP00000002745	GTP cyclohydrolase 1.	Pterin-4 alpha-carbinolamine dehydratase 1.	0.528
GCH1	PTS	ENSPPYP00000006627	ENSPPYP00000004445	GTP cyclohydrolase 1.	6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity).	0.991
GCH1	QDPR	ENSPPYP00000006627	ENSPPYP00000016338	GTP cyclohydrolase 1.	Quinoid dihydropteridine reductase.	0.602
GCHFR	ENSPPYP00000001503	ENSPPYP00000007200	ENSPPYP00000001503	GTP cyclohydrolase I feedback regulator.	annotation not available	0.442