Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYSM1MYSM1 isoform 1. (829 aa)    
Predicted Functional Partners:
CECR2
CECR2 isoform 2.
   
 0.984
KAT2B
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
   
 0.984
PSMD6
Proteasome 26S subunit, non-ATPase 6.
   
 0.889
PSMD13
PSMD13 isoform 6.
   
 0.881
PSMD4
PSMD4 isoform 1.
   
 0.880
PSMA1
Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...]
   
 0.879
ZFAND4
Zinc finger AN1-type containing 4.
   
 0.876
PSMA3
Proteasome subunit alpha type.
   
 0.876
PSMC3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
  
 0.874
PSMB2
Proteasome subunit beta.
   
 0.872
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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