Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)    
Predicted Functional Partners:
LCP1
Lymphocyte cytosolic protein 1.
      
 0.876
CTSF
CTSF isoform 1; Belongs to the peptidase C1 family.
      
 0.831
CXADR
Coxsackievirus and adenovirus receptor homolog; Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induc [...]
      
 0.828
CEACAM6
Carcinoembryonic antigen related cell adhesion molecule 6.
   
  
 0.806
IDO1
IDO1 isoform 1.
      
 0.667
CDX2
CDX2 isoform 1.
      
 0.604
KRT7
KRT7 isoform 3; Belongs to the intermediate filament family.
   
  
 0.593
ESRRB
ESRRB isoform 5.
      
 0.589
CLDN4
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
 
 0.583
BST2
BST2 isoform 1.
      
 0.583
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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