C8B protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

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Textmining

[Homology]

Score

C8B

C8B isoform 1. (592 aa)

Predicted Functional Partners:

C8G

0.977

C8A

0.953

C9

0.937

C5

0.933

C6

0.931

C7

0.929

PBX1

0.824

ECSIT

0.748

NLRP6

0.645

XPNPEP3

0.644

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5	C6	ENSPPYP00000021918	ENSPPYP00000017235	C5 isoform 1.	C6 isoform 1.	0.999
C5	C7	ENSPPYP00000021918	ENSPPYP00000017232	C5 isoform 1.	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	0.998
C5	C8A	ENSPPYP00000021918	ENSPPYP00000001517	C5 isoform 1.	Complement C8 alpha chain.	0.972
C5	C8B	ENSPPYP00000021918	ENSPPYP00000001516	C5 isoform 1.	C8B isoform 1.	0.933
C5	C8G	ENSPPYP00000021918	ENSPPYP00000022193	C5 isoform 1.	Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.	0.930
C5	C9	ENSPPYP00000021918	ENSPPYP00000017221	C5 isoform 1.	Complement C9.	0.998
C6	C5	ENSPPYP00000017235	ENSPPYP00000021918	C6 isoform 1.	C5 isoform 1.	0.999
C6	C7	ENSPPYP00000017235	ENSPPYP00000017232	C6 isoform 1.	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	0.999
C6	C8A	ENSPPYP00000017235	ENSPPYP00000001517	C6 isoform 1.	Complement C8 alpha chain.	0.938
C6	C8B	ENSPPYP00000017235	ENSPPYP00000001516	C6 isoform 1.	C8B isoform 1.	0.931
C6	C8G	ENSPPYP00000017235	ENSPPYP00000022193	C6 isoform 1.	Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.	0.971
C6	C9	ENSPPYP00000017235	ENSPPYP00000017221	C6 isoform 1.	Complement C9.	0.998
C7	C5	ENSPPYP00000017232	ENSPPYP00000021918	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	C5 isoform 1.	0.998
C7	C6	ENSPPYP00000017232	ENSPPYP00000017235	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	C6 isoform 1.	0.999
C7	C8A	ENSPPYP00000017232	ENSPPYP00000001517	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	Complement C8 alpha chain.	0.942
C7	C8B	ENSPPYP00000017232	ENSPPYP00000001516	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	C8B isoform 1.	0.929
C7	C8G	ENSPPYP00000017232	ENSPPYP00000022193	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.	0.940
C7	C9	ENSPPYP00000017232	ENSPPYP00000017221	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (By similarity).	Complement C9.	0.995
C8A	C5	ENSPPYP00000001517	ENSPPYP00000021918	Complement C8 alpha chain.	C5 isoform 1.	0.972
C8A	C6	ENSPPYP00000001517	ENSPPYP00000017235	Complement C8 alpha chain.	C6 isoform 1.	0.938