Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SCP2SCP2 isoform 1; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)    
Predicted Functional Partners:
ACOX1
Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs (By similarity). Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length (By similarity). Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs (By similarity).
  
 0.994
ACOX3
Peroxisomal acyl-coenzyme A oxidase 3; Oxidizes the CoA-esters of 2-methyl-branched fatty acids.
  
 0.983
ECI2
ECI2 isoform 1.
  
 0.983
ACAA1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
0.968
ACOT8
Acyl-CoA thioesterase 8.
   
 
 0.962
SLC27A5
Solute carrier family 27 member 5.
   
 
 0.952
HSD17B4
HSD17B4 isoform 6.
   
0.949
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.948
BAAT
Bile acid-CoA:amino acid N-acyltransferase.
   
 
 0.940
PEX5
Peroxisomal biogenesis factor 5.
   
 0.937
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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