Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TUT4ZCCHC11 isoform 3. (1640 aa)    
Predicted Functional Partners:
TUT7
ZCCHC6 isoform 2.
   
 0.884
LIN28A
LIN28A isoform 1.
    
 0.873
PAPOLG
Poly(A) polymerase gamma.
   
 
 0.735
PAPOLA
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
 
 0.707
DIS3L2
DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]
   
 
 0.674
SPEG
SPEG isoform 7.
    
 
 0.586
LIN28B
LIN28B isoform 2.
    
 0.572
MOV10
MOV10 isoform 1.
    
 
 0.553
CXorf38
Chromosome X open reading frame 38.
     
 0.512
GINM1
Glycoprotein integral membrane protein 1.
      
 0.511
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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