STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRDCNardilysin; Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. (1219 aa)    
Predicted Functional Partners:
INS-IGF2
INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.791
HBEGF
Heparin binding EGF like growth factor.
    
 
 0.749
SETX
SETX isoform 1.
      
 0.737
UBC
UBC isoform 2.
    
  0.692
SCP2
SCP2 isoform 1; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.623
TOMM70
Translocase of outer mitochondrial membrane 70.
   
 
 0.619
CR201_G0003353
RPS27A isoform 1.
    
  0.606
ENSPPYP00000023500
annotation not available
    
  0.606
ENSPPYP00000023562
annotation not available
    
  0.606
PEX13
Peroxisomal biogenesis factor 13.
   
 
  0.566
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.