Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGBL4AGBL4 isoform 1. (439 aa)    
Predicted Functional Partners:
SLC22A16
SLC22A16 isoform 2.
      
 0.844
ACTN1
ACTN1 isoform 1.
      
 0.763
CTNNA2
Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of star [...]
      
 0.758
BEND5
BEN domain containing 5.
 
  
 0.687
DPF3
DPF3 isoform 1.
      
 0.677
TRABD2B
TRABD2B isoform 1.
      
 0.653
ETV6
ETV6 isoform 1.
      
 0.633
BCL2L14
BCL2L14 isoform 3.
      
 0.626
LRATD1
LRAT domain containing 1.
      
 0.625
TRABD2A
TRABD2A isoform 1.
      
 0.622
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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