Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TMEM69TMEM69 isoform 1. (247 aa)    
Predicted Functional Partners:
GPBP1L1
Vasculin-like protein 1; Possible transcription factor; Belongs to the vasculin family.
      
 0.655
EGLN3
EGLN3 isoform 1.
    
   0.635
METAP1
Methionine aminopeptidase 1; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
   
  
 0.629
TXNDC12
Thioredoxin domain containing 12.
      
 0.628
IPO9
IPO9 isoform 1.
      
 0.531
KLHL41
Kelch repeat and BTB domain-containing protein 5/10.
      
 0.500
SPICE1
Spindle and centriole-associated protein 1; Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.
      
 0.499
C1QTNF7
C1q and TNF related 7.
      
 0.499
DYNLT1
Dynein light chain Tctex-type 1.
      
 0.486
HGSNAT
HGSNAT isoform 1.
      
 0.480
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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