Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRFPTPRF isoform 2. (1908 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.981
CTNNB1
CTNNB1 isoform 2.
   
 0.971
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
0.915
PTPN1
Tyrosine-protein phosphatase non-receptor type.
   
0.915
IRS4
Insulin receptor substrate 4.
    
 0.909
NTRK3
Tyrosine-protein kinase receptor.
   
 0.850
LRFN4
Leucine rich repeat and fibronectin type III domain containing 4.
    
 0.737
VASN
VASN isoform 1.
    
 0.701
LRRC4C
Leucine rich repeat containing 4C.
    
 0.682
ASPM
ASPM isoform 2.
    
 
 0.666
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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