Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIE1TIE1 isoform 1. (1138 aa)    
Predicted Functional Partners:
CR201_G0001936
TEK isoform 5.
   
 
 0.948
MUSK
MUSK isoform 3.
   
 0.935
ANGPT1
ANGPT1 isoform 2.
   
 0.919
ANGPT2
ANGPT2 isoform 3.
   
 0.876
ANGPT4
ANGPT4 isoform 1.
   
 0.824
NOS3
NOS3 isoform 2.
   
  
 0.807
PECAM1
PECAM1 isoform 1.
   
 0.757
PDGFC
Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 
 0.744
CDH5
CDH5 isoform 2; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.740
VEGFB
Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.
    
 0.704
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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