Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXJ3FOXJ3 isoform 1. (622 aa)    
Predicted Functional Partners:
ZNF148
Zinc finger protein 148; Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 0.719
EGR4
EGR4 isoform 1.
    
 0.702
MTF1
Metal regulatory transcription factor 1.
    
 0.642
SOX6
Transcription factor SOX-6; Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation (By similarity).
    
 
 0.611
MYB
MYB isoform 11.
    
 0.599
PLPPR1
Phospholipid phosphatase related 1.
      
 0.581
NF1
NF1 isoform 6.
   
 
 0.575
AICDA
Activation induced cytidine deaminase.
      
 0.568
BEX3
Brain expressed X-linked 3.
      
 0.559
TRPV6
TRPV6 isoform 1.
      
 0.531
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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