Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCA2BGuanylate cyclase activator 2B. (112 aa)    
Predicted Functional Partners:
GUCY2C
Guanylate cyclase.
   
 0.996
GUCA2A
Guanylate cyclase activator 2A.
  
 
0.995
RTBDN
RTBDN isoform 2.
      
 0.716
NPR3
NPR3 isoform 5.
   
 0.695
EMD
EMD isoform 1.
      
 0.656
NPR1
Guanylate cyclase.
   
 0.606
SLC51B
Solute carrier family 51 beta subunit.
   
  
 0.572
PDZD3
PDZ domain containing 3.
   
  
 0.550
OTOP2
OTOP2 isoform 2.
      
 0.524
NPR2
Guanylate cyclase.
   
 0.523
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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