Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KCNQ4KCNQ4 isoform 1; Belongs to the potassium channel family. (576 aa)    
Predicted Functional Partners:
COL10A1
Collagen type X alpha 1 chain.
      
 0.887
KCNQ1
KCNQ1 isoform 3; Belongs to the potassium channel family.
 
  
 0.874
STOX1
STOX1 isoform 1.
      
 0.850
PCDH15
PCDH15 isoform 18.
      
 0.825
OTOG
OTOG isoform 2.
   
 
 0.822
ADGRV1
ADGRV1 isoform 3; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.816
SLC17A8
Solute carrier family 17 member 8.
   
  
 0.770
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.768
USH2A
USH2A isoform 2.
    
 
 0.767
GJB3
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.766
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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