Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPT1Palmitoyl-protein thioesterase 1. (306 aa)    
Predicted Functional Partners:
PPT2
PPT2-EGFL8 isoform 1.
     
0.928
MECR
MECR isoform 4.
   
 
 0.906
SLC44A5
SLC44A5 isoform 1; Belongs to the CTL (choline transporter-like) family.
   
  
 0.893
ACSL4
ACSL4 isoform 2.
   
 
 0.840
ACSL3
Long-chain-fatty-acid--CoA ligase 3; Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta- oxidation (By similarity). ACSL3 is required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (By similarity). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity [...]
   
 
 0.840
ACSL5
ACSL5 isoform 4.
   
 
 0.836
ACSBG1
Acyl-CoA synthetase bubblegum family member 1.
   
 
 0.832
ACSBG2
ACSBG2 isoform 5.
   
 
 0.832
ACSL1
ACSL1 isoform 4.
   
 
 0.832
ACSL6
T0008628 isoform 1.
   
 
 0.832
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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