Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MANEALMannosidase endo-alpha like. (457 aa)    
Predicted Functional Partners:
ST3GAL4
ST3GAL4 isoform 10; Belongs to the glycosyltransferase 29 family.
    
   0.753
GMPS
GMP synthase [glutamine-hydrolyzing].
  
 
 0.689
RRM1
Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
     
 0.597
GRIN1
GRIN1 isoform 3.
   
 0.524
APRT
APRT isoform 1.
  
 
 0.523
EXTL1
Exostosin like glycosyltransferase 1; Belongs to the glycosyltransferase 47 family.
      
 0.486
NRSN1
NRSN1 isoform 1.
   
 
 0.482
FKRP
Fukutin related protein.
   
   0.480
TYMS
Thymidylate synthetase.
   
 
 0.463
RRM2
Ribonucleotide reductase regulatory subunit M2.
   
 
 0.463
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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