Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EVA1BEVA1B isoform 1. (167 aa)    
Predicted Functional Partners:
SLFN13
SLFN13 isoform 6.
      
 0.775
XPNPEP2
XPNPEP2 isoform 2; Belongs to the peptidase M24B family.
      
 0.726
CMPK2
CMPK2 isoform 2.
      
 0.655
NTSR1
NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.570
NTSR2
NTSR2 isoform 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.570
SLFN11
SLFN11 isoform 10.
      
 0.569
ABL2
Tyrosine-protein kinase.
      
 0.533
BDH2
3-hydroxybutyrate dehydrogenase 2.
      
 0.524
SLFN5
SLFN5 isoform 1.
      
 0.487
DECR2
Peroxisomal 2,4-dienoyl-CoA reductase; Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
      
 0.486
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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