Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADPRHL2ADP-ribosylhydrolase like 2. (364 aa)    
Predicted Functional Partners:
PARG
Poly(ADP-ribose) glycohydrolase.
      
 0.630
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
      
 0.605
MACROD1
Mono-ADP ribosylhydrolase 1.
     
 0.556
MACROD2
Mono-ADP ribosylhydrolase 2.
     
 0.523
ERLIN1
Erlin-1; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (By similarity).
   
  
 0.517
PCID2
PCI domain containing 2.
    
   0.491
OARD1
O-acyl-ADP-ribose deacylase 1.
      
 0.487
HPF1
Histone PARylation factor 1.
      
 0.475
TRPT1
tRNA phosphotransferase 1.
     
 0.446
LOC100434247
NUDT16 isoform 1.
   
  
 0.420
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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