Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIAA1522KIAA1522 isoform 2. (1033 aa)    
Predicted Functional Partners:
BAIAP2
BAI1 associated protein 2.
   
  0.916
NCK2
Cytoplasmic protein.
    
 
 0.801
WASF1
Wiskott-Aldrich syndrome protein family member 1; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity); Belongs to the SCAR/WAVE family.
    
  0.773
NCKAP1
NCK associated protein 1.
    
  0.739
ABI1
Abl interactor 1.
    
  0.713
CR201_G0042601
WASF2 isoform 2.
    
  0.697
CR201_G0042601-2
WASF2 isoform 1.
    
  0.697
NCK1
Cytoplasmic protein.
    
 
 0.682
CCNJ
CCNJ isoform 1; Belongs to the cyclin family.
    
 0.642
UNC79
UNC79 isoform 1.
    
 0.560
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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