CCDC28B protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CCDC28B

CCDC28B isoform 2. (200 aa)

Predicted Functional Partners:

WDPCP

0.584

BBS4

0.571

BBS12

0.568

BBS2

0.564

BBS7

0.562

BBS5

0.546

BBS1

0.543

TTC8

0.540

BBS10

0.534

MKS1

0.522

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS1	BBS10	ENSPPYP00000003498	ENSPPYP00000005455	T0110064 isoform 1.	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	0.805
BBS1	BBS12	ENSPPYP00000003498	ENSPPYP00000016807	T0110064 isoform 1.	Bardet-Biedl syndrome 12 protein homolog; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	0.773
BBS1	BBS2	ENSPPYP00000003498	ENSPPYP00000008322	T0110064 isoform 1.	Bardet-Biedl syndrome 2 protein homolog.	0.996
BBS1	BBS4	ENSPPYP00000003498	ENSPPYP00000007507	T0110064 isoform 1.	BBS4 isoform 3.	0.994
BBS1	BBS5	ENSPPYP00000003498	ENSPPYP00000014410	T0110064 isoform 1.	T0057746 isoform 1.	0.994
BBS1	BBS7	ENSPPYP00000003498	ENSPPYP00000016799	T0110064 isoform 1.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.997
BBS1	CCDC28B	ENSPPYP00000003498	ENSPPYP00000001846	T0110064 isoform 1.	CCDC28B isoform 2.	0.543
BBS1	MKS1	ENSPPYP00000003498	ENSPPYP00000009942	T0110064 isoform 1.	MKS1 isoform 7.	0.627
BBS1	TTC8	ENSPPYP00000003498	ENSPPYP00000006886	T0110064 isoform 1.	TTC8 isoform 1.	0.995
BBS1	WDPCP	ENSPPYP00000003498	ENSPPYP00000013798	T0110064 isoform 1.	WDPCP isoform 4.	0.520
BBS10	BBS1	ENSPPYP00000005455	ENSPPYP00000003498	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	T0110064 isoform 1.	0.805
BBS10	BBS12	ENSPPYP00000005455	ENSPPYP00000016807	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	Bardet-Biedl syndrome 12 protein homolog; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	0.969
BBS10	BBS2	ENSPPYP00000005455	ENSPPYP00000008322	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	Bardet-Biedl syndrome 2 protein homolog.	0.808
BBS10	BBS4	ENSPPYP00000005455	ENSPPYP00000007507	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	BBS4 isoform 3.	0.757
BBS10	BBS5	ENSPPYP00000005455	ENSPPYP00000014410	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	T0057746 isoform 1.	0.766
BBS10	BBS7	ENSPPYP00000005455	ENSPPYP00000016799	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.895
BBS10	CCDC28B	ENSPPYP00000005455	ENSPPYP00000001846	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	CCDC28B isoform 2.	0.534
BBS10	MKS1	ENSPPYP00000005455	ENSPPYP00000009942	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	MKS1 isoform 7.	0.656
BBS10	TTC8	ENSPPYP00000005455	ENSPPYP00000006886	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	TTC8 isoform 1.	0.709
BBS10	WDPCP	ENSPPYP00000005455	ENSPPYP00000013798	Bardet-Biedl syndrome 10 protein homolog; Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.	WDPCP isoform 4.	0.621