SPOCD1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SPOCD1

SPOCD1 isoform 1. (1095 aa)

Predicted Functional Partners:

NIPBL

0.713

ZKSCAN2

0.658

SETD2

0.612

TASOR

0.590

POLR2E

0.589

BPTF

0.583

PIN1

0.582

DNAJC9

0.569

TSPYL5

0.552

TRIP12

0.540

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPTF	NIPBL	ENSPPYP00000009623	ENSPPYP00000017209	BPTF isoform 5.	Nipped-B protein.	0.865
BPTF	SETD2	ENSPPYP00000009623	ENSPPYP00000015574	BPTF isoform 5.	SET domain containing 2, histone lysine methyltransferase.	0.853
BPTF	SPOCD1	ENSPPYP00000009623	ENSPPYP00000001853	BPTF isoform 5.	SPOCD1 isoform 1.	0.583
DNAJC9	SPOCD1	ENSPPYP00000002719	ENSPPYP00000001853	DNAJC9 isoform 1.	SPOCD1 isoform 1.	0.569
DNAJC9	TSPYL5	ENSPPYP00000002719	ENSPPYP00000021052	DNAJC9 isoform 1.	TSPYL5 isoform 1; Belongs to the nucleosome assembly protein (NAP) family.	0.516
DNAJC9	ZKSCAN2	ENSPPYP00000002719	ENSPPYP00000008148	DNAJC9 isoform 1.	ZKSCAN2 isoform 1.	0.671
NIPBL	BPTF	ENSPPYP00000017209	ENSPPYP00000009623	Nipped-B protein.	BPTF isoform 5.	0.865
NIPBL	SETD2	ENSPPYP00000017209	ENSPPYP00000015574	Nipped-B protein.	SET domain containing 2, histone lysine methyltransferase.	0.867
NIPBL	SPOCD1	ENSPPYP00000017209	ENSPPYP00000001853	Nipped-B protein.	SPOCD1 isoform 1.	0.713
NIPBL	TASOR	ENSPPYP00000017209	ENSPPYP00000015415	Nipped-B protein.	FAM208A isoform 4.	0.432
NIPBL	TRIP12	ENSPPYP00000017209	ENSPPYP00000014809	Nipped-B protein.	TRIP12 isoform 4.	0.761
PIN1	SPOCD1	ENSPPYP00000010696	ENSPPYP00000001853	Peptidyl-prolyl cis-trans isomerase.	SPOCD1 isoform 1.	0.582
POLR2E	SETD2	ENSPPYP00000010442	ENSPPYP00000015574	DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the [...]	SET domain containing 2, histone lysine methyltransferase.	0.744
POLR2E	SPOCD1	ENSPPYP00000010442	ENSPPYP00000001853	DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the [...]	SPOCD1 isoform 1.	0.589
SETD2	BPTF	ENSPPYP00000015574	ENSPPYP00000009623	SET domain containing 2, histone lysine methyltransferase.	BPTF isoform 5.	0.853
SETD2	NIPBL	ENSPPYP00000015574	ENSPPYP00000017209	SET domain containing 2, histone lysine methyltransferase.	Nipped-B protein.	0.867
SETD2	POLR2E	ENSPPYP00000015574	ENSPPYP00000010442	SET domain containing 2, histone lysine methyltransferase.	DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the [...]	0.744
SETD2	SPOCD1	ENSPPYP00000015574	ENSPPYP00000001853	SET domain containing 2, histone lysine methyltransferase.	SPOCD1 isoform 1.	0.612
SETD2	TRIP12	ENSPPYP00000015574	ENSPPYP00000014809	SET domain containing 2, histone lysine methyltransferase.	TRIP12 isoform 4.	0.687
SPOCD1	BPTF	ENSPPYP00000001853	ENSPPYP00000009623	SPOCD1 isoform 1.	BPTF isoform 5.	0.583