Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PEF1Penta-EF-hand domain containing 1. (284 aa)    
Predicted Functional Partners:
PDCD6
Programmed cell death protein 6 isoform X1.
   
0.946
KLHL12
KLHL12 isoform 2.
    
 0.931
SEC31A
Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
    
 0.843
PDCD6IP
PDCD6IP isoform 2.
    
 
 0.819
SEC31B
LOW QUALITY PROTEIN: protein transport protein Sec31B.
    
 0.767
FOXR2
FOXR2 isoform 1.
    
   0.736
ANXA11
Annexin.
   
 
 0.729
SEC23IP
SEC23IP isoform 1.
    
 
 0.719
HEBP2
HEBP2 isoform 2.
   
 
 0.707
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.703
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (30%) [HD]