LAPTM5 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LAPTM5

Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells. (262 aa)

Predicted Functional Partners:

C1QC

0.995

LAPTM4B

0.915

CD53

0.910

LAPTM4A

0.908

HCLS1

0.849

ITGB2

0.843

NEDD4

0.788

LY86

0.774

NCKAP1L

0.758

TYROBP

0.753

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QC	LAPTM5	ENSPPYP00000002025	ENSPPYP00000001875	Complement C1q C chain.	Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells.	0.995
C1QC	LY86	ENSPPYP00000002025	ENSPPYP00000018121	Complement C1q C chain.	LY86 isoform 1.	0.603
C1QC	TYROBP	ENSPPYP00000002025	ENSPPYP00000011071	Complement C1q C chain.	TYRO protein tyrosine kinase binding protein.	0.537
CD53	ITGB2	ENSPPYP00000001212	ENSPPYP00000012844	Tetraspanin.	Integrin beta.	0.665
CD53	LAPTM5	ENSPPYP00000001212	ENSPPYP00000001875	Tetraspanin.	Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells.	0.910
CD53	LY86	ENSPPYP00000001212	ENSPPYP00000018121	Tetraspanin.	LY86 isoform 1.	0.450
CD53	NCKAP1L	ENSPPYP00000001212	ENSPPYP00000005254	Tetraspanin.	NCK associated protein 1 like.	0.422
CD53	TYROBP	ENSPPYP00000001212	ENSPPYP00000011071	Tetraspanin.	TYRO protein tyrosine kinase binding protein.	0.481
HCLS1	ITGB2	ENSPPYP00000015093	ENSPPYP00000012844	HCLS1 isoform 5.	Integrin beta.	0.561
HCLS1	LAPTM5	ENSPPYP00000015093	ENSPPYP00000001875	HCLS1 isoform 5.	Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells.	0.849
ITGB2	CD53	ENSPPYP00000012844	ENSPPYP00000001212	Integrin beta.	Tetraspanin.	0.665
ITGB2	HCLS1	ENSPPYP00000012844	ENSPPYP00000015093	Integrin beta.	HCLS1 isoform 5.	0.561
ITGB2	LAPTM5	ENSPPYP00000012844	ENSPPYP00000001875	Integrin beta.	Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells.	0.843
ITGB2	NCKAP1L	ENSPPYP00000012844	ENSPPYP00000005254	Integrin beta.	NCK associated protein 1 like.	0.591
ITGB2	TYROBP	ENSPPYP00000012844	ENSPPYP00000011071	Integrin beta.	TYRO protein tyrosine kinase binding protein.	0.938
LAPTM4A	LAPTM4B	ENSPPYP00000014092	ENSPPYP00000021054	Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.	LAPTM4B isoform 1.	0.911
LAPTM4A	LAPTM5	ENSPPYP00000014092	ENSPPYP00000001875	Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.	Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells.	0.908
LAPTM4A	NEDD4	ENSPPYP00000014092	ENSPPYP00000007372	Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.	E3 ubiquitin-protein ligase.	0.755
LAPTM4B	LAPTM4A	ENSPPYP00000021054	ENSPPYP00000014092	LAPTM4B isoform 1.	Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.	0.911
LAPTM4B	LAPTM5	ENSPPYP00000021054	ENSPPYP00000001875	LAPTM4B isoform 1.	Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells.	0.915

page 1 of 3

Server load: low (8%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About