PPP1R8 protein (Pongo abelii) - STRING interaction network

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Score

PPP1R8

Protein phosphatase 1 regulatory subunit 8. (351 aa)

Predicted Functional Partners:

PPP1CC

0.945

TCERG1

0.929

SUGP1

0.923

CDC40

0.923

PPP1R11

0.916

RBM39

0.913

DHX9

0.885

PPP1CA

0.871

SRRT

0.867

PRPF40A

0.861

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC40	DHX9	ENSPPYP00000018941	ENSPPYP00000000490	CDC40 isoform 1.	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	0.917
CDC40	PPP1R8	ENSPPYP00000018941	ENSPPYP00000001910	CDC40 isoform 1.	Protein phosphatase 1 regulatory subunit 8.	0.923
CDC40	PRPF40A	ENSPPYP00000018941	ENSPPYP00000014347	CDC40 isoform 1.	PRPF40A isoform 2.	0.869
CDC40	RBM39	ENSPPYP00000018941	ENSPPYP00000012240	CDC40 isoform 1.	RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.	0.953
CDC40	SRRT	ENSPPYP00000018941	ENSPPYP00000019542	CDC40 isoform 1.	Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. [...]	0.867
CDC40	SUGP1	ENSPPYP00000018941	ENSPPYP00000010938	CDC40 isoform 1.	SUGP1 isoform 1.	0.925
CDC40	TCERG1	ENSPPYP00000018941	ENSPPYP00000017799	CDC40 isoform 1.	TCERG1 isoform 1.	0.968
DHX9	CDC40	ENSPPYP00000000490	ENSPPYP00000018941	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	CDC40 isoform 1.	0.917
DHX9	PPP1R8	ENSPPYP00000000490	ENSPPYP00000001910	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	Protein phosphatase 1 regulatory subunit 8.	0.885
DHX9	PRPF40A	ENSPPYP00000000490	ENSPPYP00000014347	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	PRPF40A isoform 2.	0.893
DHX9	RBM39	ENSPPYP00000000490	ENSPPYP00000012240	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.	0.903
DHX9	SRRT	ENSPPYP00000000490	ENSPPYP00000019542	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. [...]	0.904
DHX9	SUGP1	ENSPPYP00000000490	ENSPPYP00000010938	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	SUGP1 isoform 1.	0.877
DHX9	TCERG1	ENSPPYP00000000490	ENSPPYP00000017799	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	TCERG1 isoform 1.	0.875
PPP1CA	PPP1CC	ENSPPYP00000003472	ENSPPYP00000005654	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.999
PPP1CA	PPP1R11	ENSPPYP00000003472	ENSPPYP00000023843	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	PPP1R11 isoform 1.	0.854
PPP1CA	PPP1R8	ENSPPYP00000003472	ENSPPYP00000001910	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Protein phosphatase 1 regulatory subunit 8.	0.871
PPP1CC	PPP1CA	ENSPPYP00000005654	ENSPPYP00000003472	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.999
PPP1CC	PPP1R11	ENSPPYP00000005654	ENSPPYP00000023843	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	PPP1R11 isoform 1.	0.954
PPP1CC	PPP1R8	ENSPPYP00000005654	ENSPPYP00000001910	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Protein phosphatase 1 regulatory subunit 8.	0.945