Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GPR3G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)    
Predicted Functional Partners:
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.772
GNB2
GNB2 isoform 1.
    
  0.713
GNG4
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.653
NPR2
Guanylate cyclase.
     
 0.531
PDE3A
Phosphodiesterase.
      
 0.530
GPR39
GPR39 isoform 1; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.519
GPR31
G protein-coupled receptor 31; Belongs to the G-protein coupled receptor 1 family.
     
 0.514
DMWD
Dystrophia myotonica WD repeat-containing protein isoform X1.
    
  0.496
GPR87
G protein-coupled receptor 87; Belongs to the G-protein coupled receptor 1 family.
      
 0.486
NCOA7
NCOA7 isoform 1.
   
  
 0.469
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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