Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FCN3FCN3 isoform 1. (308 aa)    
Predicted Functional Partners:
MASP1
MASP1 isoform 1.
   
 0.976
CYP4V2
Cytochrome P450 4V2; Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye. Catalyzes the omega- hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22- hydroxydocosahexaenoate. Also produces some 2 [...]
   
 0.854
MASP2
MASP2 isoform 1; Belongs to the peptidase S1 family.
   
 0.851
PTX3
PTX3 isoform 1.
    
 
 0.704
C1R
Complement C1r subcomponent heavy chain; C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system; Belongs to the peptidase S1 family.
   
 0.661
MBL2
MBL2 isoform 1.
   
 0.656
FCN2
FCN2 isoform 2.
  
0.654
C1S
C1S isoform 1; Belongs to the peptidase S1 family.
   
 0.650
ENSPPYP00000023939
LOW QUALITY PROTEIN: complement C1s subcomponent-like.
   
 0.650
FCN1
FCN1 isoform 1.
  
 
0.639
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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