Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYTL1Synaptotagmin like 1. (550 aa)    
Predicted Functional Partners:
RAB27A
RAB27A, member RAS oncogene family.
   
 0.979
RAB27B
RAB27B, member RAS oncogene family.
   
 0.977
TBC1D10A
TBC1 domain family member 10A.
     
 0.931
TBC1D10B
TBC1 domain family member 10B.
     
 0.768
MYRIP
MYRIP isoform 1.
     
 0.744
MYO5A
MYO5A isoform 5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.638
STK33
Serine/threonine kinase 33.
   
  
 0.636
CCDC60
Coiled-coil domain containing 60.
      
 0.632
SDR42E1
Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family.
      
 0.611
CPNE6
Copine-6; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity). Plays a role in dendrite formation by melanocytes (By similarity). Belongs to the copine family.
      
 0.588
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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