Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KDF1KDF1 isoform 1. (395 aa)    
Predicted Functional Partners:
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 
 0.591
GRHL3
GRHL3 isoform 2.
   
  
 0.510
RAB25
RAB25, member RAS oncogene family.
   
  
 0.505
TMEM222
TMEM222 isoform 3.
      
 0.501
EDARADD
EDAR associated death domain.
      
 0.461
IRF6
IRF6 isoform 2.
   
  
 0.417
C1orf210
Chromosome 1 open reading frame 210.
   
  
 0.414
SFN
SFN isoform 1; Belongs to the 14-3-3 family.
      
 0.409
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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