Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPATCH3G-patch domain containing 3. (525 aa)    
Predicted Functional Partners:
ZNF408
ZNF408 isoform 1.
   
    0.950
EFCAB1
EF-hand calcium binding domain 1.
      
 0.623
ARL2BP
ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity).
      
 0.622
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
      
 0.620
RSPRY1
RING finger and SPRY domain-containing protein 1.
      
 0.617
PLEKHA8
Pleckstrin homology domain containing A8.
   
  
 0.616
EAF1
ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
      
 0.596
ZNRF2
E3 ubiquitin-protein ligase ZNRF1/2.
      
 0.570
METTL6
tRNA N(3)-methylcytidine methyltransferase METTL6; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser).
      
 0.547
EDC3
Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity); Belongs to the EDC3 family.
   
  
 0.532
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (18%) [HD]