GPN2 protein (Pongo abelii) - STRING interaction network

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GPN2

GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (310 aa)

Predicted Functional Partners:

RPAP1

0.975

GPN1

0.968

POLR2L

0.958

POLR2B

0.946

POLR2C

0.863

ENSPPYP00000007380

0.820

GPN3

0.790

RPAP2

0.680

TMEM35B

0.674

UROS

0.664

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000007380	GPN1	ENSPPYP00000007380	ENSPPYP00000014003	annotation not available	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	0.817
ENSPPYP00000007380	GPN2	ENSPPYP00000007380	ENSPPYP00000001936	annotation not available	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.820
ENSPPYP00000007380	GPN3	ENSPPYP00000007380	ENSPPYP00000005646	annotation not available	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.775
ENSPPYP00000007380	POLR2B	ENSPPYP00000007380	ENSPPYP00000016468	annotation not available	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.852
ENSPPYP00000007380	POLR2C	ENSPPYP00000007380	ENSPPYP00000008349	annotation not available	RNA polymerase II subunit C.	0.820
ENSPPYP00000007380	POLR2L	ENSPPYP00000007380	ENSPPYP00000024243	annotation not available	POLR2L isoform 1.	0.814
ENSPPYP00000007380	RPAP1	ENSPPYP00000007380	ENSPPYP00000007224	annotation not available	RPAP1 isoform 3.	0.796
ENSPPYP00000007380	RPAP2	ENSPPYP00000007380	ENSPPYP00000001338	annotation not available	Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.	0.845
GPN1	ENSPPYP00000007380	ENSPPYP00000014003	ENSPPYP00000007380	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	annotation not available	0.817
GPN1	GPN2	ENSPPYP00000014003	ENSPPYP00000001936	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.968
GPN1	GPN3	ENSPPYP00000014003	ENSPPYP00000005646	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.940
GPN1	POLR2B	ENSPPYP00000014003	ENSPPYP00000016468	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.887
GPN1	POLR2C	ENSPPYP00000014003	ENSPPYP00000008349	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	RNA polymerase II subunit C.	0.860
GPN1	POLR2L	ENSPPYP00000014003	ENSPPYP00000024243	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	POLR2L isoform 1.	0.822
GPN1	RPAP1	ENSPPYP00000014003	ENSPPYP00000007224	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	RPAP1 isoform 3.	0.972
GPN1	RPAP2	ENSPPYP00000014003	ENSPPYP00000001338	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.	0.975
GPN2	ENSPPYP00000007380	ENSPPYP00000001936	ENSPPYP00000007380	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	annotation not available	0.820
GPN2	GPN1	ENSPPYP00000001936	ENSPPYP00000014003	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	0.968
GPN2	GPN3	ENSPPYP00000001936	ENSPPYP00000005646	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.790
GPN2	POLR2B	ENSPPYP00000001936	ENSPPYP00000016468	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.946

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