DHDDS protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

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Score

DHDDS

Alkyl transferase; Belongs to the UPP synthase family. (333 aa)

Predicted Functional Partners:

NUS1-2

0.997

NUS1

0.980

GGPS1

0.948

PDSS1

0.947

FDPS

0.946

PDSS2

0.946

FDFT1

0.843

IDI1

0.803

COQ2

0.799

UBIAD1

0.763

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ2	DHDDS	ENSPPYP00000023711	ENSPPYP00000001944	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Alkyl transferase; Belongs to the UPP synthase family.	0.799
COQ2	FDFT1	ENSPPYP00000023711	ENSPPYP00000020559	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family.	0.613
COQ2	FDPS	ENSPPYP00000023711	ENSPPYP00000000868	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	FDPS isoform 12; Belongs to the FPP/GGPP synthase family.	0.638
COQ2	GGPS1	ENSPPYP00000023711	ENSPPYP00000000097	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	0.701
COQ2	IDI1	ENSPPYP00000023711	ENSPPYP00000002358	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).	0.941
COQ2	NUS1	ENSPPYP00000023711	ENSPPYP00000023514	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	NUS1 dehydrodolichyl diphosphate synthase subunit.	0.799
COQ2	NUS1-2	ENSPPYP00000023711	ENSPPYP00000006789	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Uncharacterized protein.	0.799
COQ2	PDSS1	ENSPPYP00000023711	ENSPPYP00000002513	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.	0.980
COQ2	PDSS2	ENSPPYP00000023711	ENSPPYP00000018906	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	PDSS2 isoform 2; Belongs to the FPP/GGPP synthase family.	0.980
COQ2	UBIAD1	ENSPPYP00000023711	ENSPPYP00000021525	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	UBIAD1 isoform 1.	0.918
DHDDS	COQ2	ENSPPYP00000001944	ENSPPYP00000023711	Alkyl transferase; Belongs to the UPP synthase family.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.799
DHDDS	FDFT1	ENSPPYP00000001944	ENSPPYP00000020559	Alkyl transferase; Belongs to the UPP synthase family.	Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family.	0.843
DHDDS	FDPS	ENSPPYP00000001944	ENSPPYP00000000868	Alkyl transferase; Belongs to the UPP synthase family.	FDPS isoform 12; Belongs to the FPP/GGPP synthase family.	0.946
DHDDS	GGPS1	ENSPPYP00000001944	ENSPPYP00000000097	Alkyl transferase; Belongs to the UPP synthase family.	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	0.948
DHDDS	IDI1	ENSPPYP00000001944	ENSPPYP00000002358	Alkyl transferase; Belongs to the UPP synthase family.	Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).	0.803
DHDDS	NUS1	ENSPPYP00000001944	ENSPPYP00000023514	Alkyl transferase; Belongs to the UPP synthase family.	NUS1 dehydrodolichyl diphosphate synthase subunit.	0.980
DHDDS	NUS1-2	ENSPPYP00000001944	ENSPPYP00000006789	Alkyl transferase; Belongs to the UPP synthase family.	Uncharacterized protein.	0.997
DHDDS	PDSS1	ENSPPYP00000001944	ENSPPYP00000002513	Alkyl transferase; Belongs to the UPP synthase family.	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.	0.947
DHDDS	PDSS2	ENSPPYP00000001944	ENSPPYP00000018906	Alkyl transferase; Belongs to the UPP synthase family.	PDSS2 isoform 2; Belongs to the FPP/GGPP synthase family.	0.946
DHDDS	UBIAD1	ENSPPYP00000001944	ENSPPYP00000021525	Alkyl transferase; Belongs to the UPP synthase family.	UBIAD1 isoform 1.	0.763