Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD52CD52 isoform 1. (61 aa)    
Predicted Functional Partners:
CD3E
CD3E isoform 2.
   
  
 0.865
CD2
CD2 isoform 1.
   
  
 0.762
CORO1A
Coronin; Belongs to the WD repeat coronin family.
   
  
 0.733
CD4
CD4 isoform 2.
      
 0.729
CD53
Tetraspanin.
   
  
 0.703
SIGLEC10
Sialic acid binding Ig like lectin 10.
   
 0.674
CD48
CD48 isoform 1.
   
  
 0.602
SEPT1
SEPT1 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
   
    0.585
SIGLEC11
SIGLEC11 isoform 2.
   
 0.569
S100A16
Protein S100; Belongs to the S-100 family.
   
  
 0.523
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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