Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STMN1Stathmin; Belongs to the stathmin family. (149 aa)    
Predicted Functional Partners:
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.940
TUBA1B
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
   
 0.828
STMN4
Stathmin-4; Exhibits microtubule-destabilizing activity; Belongs to the stathmin family.
    
   0.798
ENSPPYP00000004309
annotation not available
   
 0.771
NISCH
NISCH isoform 1.
      
 0.761
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.747
STMN3
Stathmin-3; Exhibits microtubule-destabilizing activity, which is antagonized by STAT3; Belongs to the stathmin family.
    
   0.711
MAZ
MAZ isoform 8.
    
 0.677
STIP1
STIP1 isoform 2.
   
 0.634
CDK4
CDK4 isoform 2; Belongs to the protein kinase superfamily.
   
 0.625
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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