Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AUNIPAUNIP isoform 2. (332 aa)    
Predicted Functional Partners:
AURKA
AURKA isoform 10; Belongs to the protein kinase superfamily.
   
 
 0.761
ZNF750
Zinc finger protein 750.
      
 0.618
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
   
  
 0.585
DTL
DTL isoform 2.
   
  
 0.562
AURKB
AURKB isoform 2; Belongs to the protein kinase superfamily.
   
 
 0.458
AURKC
AURKC isoform 3; Belongs to the protein kinase superfamily.
   
 
 0.448
TINF2
TINF2 isoform 1.
  
     0.439
EIPR1
EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome- associated recycling protein (EARP) complex.
      
 0.422
ANLN
ANLN isoform 2.
   
  
 0.421
ECT2
ECT2 isoform 4.
   
  
 0.420
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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