| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALYREF | CR201_G0006690 | ENSPPYP00000009820 | ENSPPYP00000023142 | Aly/REF export factor. | UPF3B isoform 4. | 0.955 |
| ALYREF | EIF4A3 | ENSPPYP00000009820 | ENSPPYP00000009779 | Aly/REF export factor. | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | 0.995 |
| ALYREF | NXF1 | ENSPPYP00000009820 | ENSPPYP00000003631 | Aly/REF export factor. | Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1- NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A- containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A- containing mRNA-binding to both [...] | 0.992 |
| ALYREF | PPIG | ENSPPYP00000009820 | ENSPPYP00000014414 | Aly/REF export factor. | PPIG isoform 1. | 0.823 |
| ALYREF | SRRM1 | ENSPPYP00000009820 | ENSPPYP00000001983 | Aly/REF export factor. | Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] | 0.984 |
| ALYREF | SRRM2 | ENSPPYP00000009820 | ENSPPYP00000007933 | Aly/REF export factor. | SRRM2 isoform 1. | 0.704 |
| ALYREF | SRRM3 | ENSPPYP00000009820 | ENSPPYP00000019584 | Aly/REF export factor. | SRRM3 isoform 1. | 0.704 |
| ALYREF | UPF1 | ENSPPYP00000009820 | ENSPPYP00000010923 | Aly/REF export factor. | UPF1 isoform 2. | 0.949 |
| ALYREF | UPF2 | ENSPPYP00000009820 | ENSPPYP00000002423 | Aly/REF export factor. | UPF2 isoform 1. | 0.600 |
| ALYREF | UPF3A | ENSPPYP00000009820 | ENSPPYP00000006310 | Aly/REF export factor. | UPF3A regulator of nonsense mediated mRNA decay. | 0.987 |
| CR201_G0006690 | ALYREF | ENSPPYP00000023142 | ENSPPYP00000009820 | UPF3B isoform 4. | Aly/REF export factor. | 0.955 |
| CR201_G0006690 | EIF4A3 | ENSPPYP00000023142 | ENSPPYP00000009779 | UPF3B isoform 4. | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | 0.977 |
| CR201_G0006690 | NXF1 | ENSPPYP00000023142 | ENSPPYP00000003631 | UPF3B isoform 4. | Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1- NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A- containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A- containing mRNA-binding to both [...] | 0.965 |
| CR201_G0006690 | PPIG | ENSPPYP00000023142 | ENSPPYP00000014414 | UPF3B isoform 4. | PPIG isoform 1. | 0.622 |
| CR201_G0006690 | SRRM1 | ENSPPYP00000023142 | ENSPPYP00000001983 | UPF3B isoform 4. | Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] | 0.941 |
| CR201_G0006690 | SRRM2 | ENSPPYP00000023142 | ENSPPYP00000007933 | UPF3B isoform 4. | SRRM2 isoform 1. | 0.514 |
| CR201_G0006690 | SRRM3 | ENSPPYP00000023142 | ENSPPYP00000019584 | UPF3B isoform 4. | SRRM3 isoform 1. | 0.404 |
| CR201_G0006690 | UPF1 | ENSPPYP00000023142 | ENSPPYP00000010923 | UPF3B isoform 4. | UPF1 isoform 2. | 0.994 |
| CR201_G0006690 | UPF2 | ENSPPYP00000023142 | ENSPPYP00000002423 | UPF3B isoform 4. | UPF2 isoform 1. | 0.993 |
| CR201_G0006690 | UPF3A | ENSPPYP00000023142 | ENSPPYP00000006310 | UPF3B isoform 4. | UPF3A regulator of nonsense mediated mRNA decay. | 0.916 |
