Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRHL3GRHL3 isoform 2. (602 aa)    
Predicted Functional Partners:
ARHGAP29
ARHGAP29 isoform 3.
      
 0.576
ZNF750
Zinc finger protein 750.
   
  
 0.548
HOXB6
HOXB6 isoform 1.
    
 
 0.545
GLI3
GLI3 isoform 3.
    
 
 0.535
TGM1
TGM1 isoform 5.
   
  
 0.528
KDF1
KDF1 isoform 1.
   
  
 0.510
OVOL1
OVOL1 isoform 1.
   
  
 0.493
IRF5
IRF5 isoform 3.
   
 
 0.489
IRF6
IRF6 isoform 2.
   
 
 0.488
SPATA4
SPATA4 isoform 1.
      
 0.472
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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