PNRC2 protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

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Score

PNRC2

Proline rich nuclear receptor coactivator 2. (139 aa)

Predicted Functional Partners:

DCP1A

0.985

ENSPPYP00000017543

0.880

UPF1

0.841

SMG5

0.806

DCP1B

0.760

ESRRG

0.717

SMG7

0.702

SMG6

0.669

SMG9

0.669

UPF2

0.640

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCP1A	DCP1B	ENSPPYP00000015428	ENSPPYP00000004723	DCP1A isoform 1.	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	0.998
DCP1A	ENSPPYP00000017543	ENSPPYP00000015428	ENSPPYP00000017543	DCP1A isoform 1.	annotation not available	0.999
DCP1A	PNRC2	ENSPPYP00000015428	ENSPPYP00000001999	DCP1A isoform 1.	Proline rich nuclear receptor coactivator 2.	0.985
DCP1A	SMG5	ENSPPYP00000015428	ENSPPYP00000000838	DCP1A isoform 1.	SMG5 nonsense mediated mRNA decay factor.	0.791
DCP1A	SMG6	ENSPPYP00000015428	ENSPPYP00000008776	DCP1A isoform 1.	Telomerase-binding protein EST1A; Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER).	0.727
DCP1A	SMG7	ENSPPYP00000015428	ENSPPYP00000000485	DCP1A isoform 1.	SMG7 nonsense mediated mRNA decay factor.	0.731
DCP1A	SMG9	ENSPPYP00000015428	ENSPPYP00000023744	DCP1A isoform 1.	SMG9 nonsense mediated mRNA decay factor.	0.617
DCP1A	UPF1	ENSPPYP00000015428	ENSPPYP00000010923	DCP1A isoform 1.	UPF1 isoform 2.	0.956
DCP1A	UPF2	ENSPPYP00000015428	ENSPPYP00000002423	DCP1A isoform 1.	UPF2 isoform 1.	0.581
DCP1B	DCP1A	ENSPPYP00000004723	ENSPPYP00000015428	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	DCP1A isoform 1.	0.998
DCP1B	ENSPPYP00000017543	ENSPPYP00000004723	ENSPPYP00000017543	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	annotation not available	0.993
DCP1B	PNRC2	ENSPPYP00000004723	ENSPPYP00000001999	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Proline rich nuclear receptor coactivator 2.	0.760
DCP1B	SMG5	ENSPPYP00000004723	ENSPPYP00000000838	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	SMG5 nonsense mediated mRNA decay factor.	0.437
DCP1B	SMG6	ENSPPYP00000004723	ENSPPYP00000008776	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Telomerase-binding protein EST1A; Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER).	0.437
DCP1B	SMG7	ENSPPYP00000004723	ENSPPYP00000000485	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	SMG7 nonsense mediated mRNA decay factor.	0.437
DCP1B	SMG9	ENSPPYP00000004723	ENSPPYP00000023744	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	SMG9 nonsense mediated mRNA decay factor.	0.474
DCP1B	UPF1	ENSPPYP00000004723	ENSPPYP00000010923	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	UPF1 isoform 2.	0.811
DCP1B	UPF2	ENSPPYP00000004723	ENSPPYP00000002423	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	UPF2 isoform 1.	0.520
ENSPPYP00000017543	DCP1A	ENSPPYP00000017543	ENSPPYP00000015428	annotation not available	DCP1A isoform 1.	0.999
ENSPPYP00000017543	DCP1B	ENSPPYP00000017543	ENSPPYP00000004723	annotation not available	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	0.993