ZNF436 protein (Pongo abelii) - STRING interaction network

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ZNF436

Zinc finger protein 436; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (470 aa)

Predicted Functional Partners:

ZUP1

0.610

TRIM28

0.547

USP5

0.533

SETDB2

0.529

UBC

0.527

USP44

0.524

YOD1

0.516

SUPT5H

0.509

TADA3

0.509

ZMYM6

0.503

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SETDB2	SUPT5H	ENSPPYP00000006116	ENSPPYP00000011160	SETDB2 isoform 3.	Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...]	0.558
SETDB2	TADA3	ENSPPYP00000006116	ENSPPYP00000015293	SETDB2 isoform 3.	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	0.492
SETDB2	TRIM28	ENSPPYP00000006116	ENSPPYP00000011777	SETDB2 isoform 3.	TRIM28 isoform 3.	0.700
SETDB2	ZMYM6	ENSPPYP00000006116	ENSPPYP00000001804	SETDB2 isoform 3.	Zinc finger MYM-type protein 6.	0.557
SETDB2	ZNF436	ENSPPYP00000006116	ENSPPYP00000002018	SETDB2 isoform 3.	Zinc finger protein 436; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.529
SUPT5H	SETDB2	ENSPPYP00000011160	ENSPPYP00000006116	Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...]	SETDB2 isoform 3.	0.558
SUPT5H	TADA3	ENSPPYP00000011160	ENSPPYP00000015293	Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...]	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	0.481
SUPT5H	ZMYM6	ENSPPYP00000011160	ENSPPYP00000001804	Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...]	Zinc finger MYM-type protein 6.	0.515
SUPT5H	ZNF436	ENSPPYP00000011160	ENSPPYP00000002018	Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...]	Zinc finger protein 436; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.509
TADA3	SETDB2	ENSPPYP00000015293	ENSPPYP00000006116	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	SETDB2 isoform 3.	0.492
TADA3	SUPT5H	ENSPPYP00000015293	ENSPPYP00000011160	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote paus [...]	0.481
TADA3	UBC	ENSPPYP00000015293	ENSPPYP00000005811	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	UBC isoform 2.	0.400
TADA3	USP44	ENSPPYP00000015293	ENSPPYP00000005527	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.665
TADA3	ZMYM6	ENSPPYP00000015293	ENSPPYP00000001804	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	Zinc finger MYM-type protein 6.	0.514
TADA3	ZNF436	ENSPPYP00000015293	ENSPPYP00000002018	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	Zinc finger protein 436; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.509
TRIM28	SETDB2	ENSPPYP00000011777	ENSPPYP00000006116	TRIM28 isoform 3.	SETDB2 isoform 3.	0.700
TRIM28	UBC	ENSPPYP00000011777	ENSPPYP00000005811	TRIM28 isoform 3.	UBC isoform 2.	0.820
TRIM28	ZNF436	ENSPPYP00000011777	ENSPPYP00000002018	TRIM28 isoform 3.	Zinc finger protein 436; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.547
UBC	TADA3	ENSPPYP00000005811	ENSPPYP00000015293	UBC isoform 2.	Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).	0.400
UBC	TRIM28	ENSPPYP00000005811	ENSPPYP00000011777	UBC isoform 2.	TRIM28 isoform 3.	0.820

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