node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | SZRD1 | ENSPPYP00000010804 | ENSPPYP00000002114 | ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family. | SUZ domain-containing protein 1. | 0.893 |
ADGRL2 | SZRD1 | ENSPPYP00000001403 | ENSPPYP00000002114 | ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family. | SUZ domain-containing protein 1. | 0.893 |
ADGRL3 | SZRD1 | ENSPPYP00000016465 | ENSPPYP00000002114 | ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family. | SUZ domain-containing protein 1. | 0.893 |
MTHFSD | NOP56 | ENSPPYP00000008601 | ENSPPYP00000012104 | MTHFSD isoform 6. | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | 0.782 |
MTHFSD | PSMD1 | ENSPPYP00000008601 | ENSPPYP00000014825 | MTHFSD isoform 6. | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.689 |
MTHFSD | SMC1B | ENSPPYP00000008601 | ENSPPYP00000013319 | MTHFSD isoform 6. | Structural maintenance of chromosomes protein. | 0.543 |
MTHFSD | SNU13 | ENSPPYP00000008601 | ENSPPYP00000013255 | MTHFSD isoform 6. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.769 |
MTHFSD | SZRD1 | ENSPPYP00000008601 | ENSPPYP00000002114 | MTHFSD isoform 6. | SUZ domain-containing protein 1. | 0.677 |
MTHFSD | UTP15 | ENSPPYP00000008601 | ENSPPYP00000017381 | MTHFSD isoform 6. | U3 small nucleolar RNA-associated protein 15 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. | 0.755 |
NOP56 | MTHFSD | ENSPPYP00000012104 | ENSPPYP00000008601 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | MTHFSD isoform 6. | 0.782 |
NOP56 | PSMD1 | ENSPPYP00000012104 | ENSPPYP00000014825 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.698 |
NOP56 | SMC1B | ENSPPYP00000012104 | ENSPPYP00000013319 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | Structural maintenance of chromosomes protein. | 0.538 |
NOP56 | SNU13 | ENSPPYP00000012104 | ENSPPYP00000013255 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.999 |
NOP56 | SZRD1 | ENSPPYP00000012104 | ENSPPYP00000002114 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | SUZ domain-containing protein 1. | 0.437 |
NOP56 | UTP15 | ENSPPYP00000012104 | ENSPPYP00000017381 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | U3 small nucleolar RNA-associated protein 15 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. | 0.996 |
PSMD1 | MTHFSD | ENSPPYP00000014825 | ENSPPYP00000008601 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | MTHFSD isoform 6. | 0.689 |
PSMD1 | NOP56 | ENSPPYP00000014825 | ENSPPYP00000012104 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). | 0.698 |
PSMD1 | SMC1B | ENSPPYP00000014825 | ENSPPYP00000013319 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | Structural maintenance of chromosomes protein. | 0.537 |
PSMD1 | SNU13 | ENSPPYP00000014825 | ENSPPYP00000013255 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.738 |
PSMD1 | SZRD1 | ENSPPYP00000014825 | ENSPPYP00000002114 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | SUZ domain-containing protein 1. | 0.671 |