Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSPB7HSPB7 isoform 4; Belongs to the small heat shock protein (HSP20) family. (172 aa)    
Predicted Functional Partners:
ARL13A
ARL13A isoform 3.
      
 0.872
FLNA
FLNA isoform 7.
   
 
 0.866
HSPB3
Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family.
   
  
 0.829
HSPB2
HSPB2-C11orf52 isoform 2; Belongs to the small heat shock protein (HSP20) family.
  
  
0.828
TNFSF18
TNFSF18 isoform 1.
      
 0.822
FLNC
FLNC isoform 2.
   
 
 0.820
BAG3
BAG3 isoform 1.
   
 
 0.669
MYOZ2
Myozenin-2; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis (By similarity).
   
 
 0.641
MAGEC2
MAGE family member C2.
      
 0.604
CYLC1
CYLC1 isoform 2.
    
 
 0.596
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.