| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGMAT | ALDH1B1 | ENSPPYP00000002136 | ENSPPYP00000021352 | AGMAT isoform 1; Belongs to the arginase family. | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | 0.923 |
| AGMAT | ALDH2 | ENSPPYP00000002136 | ENSPPYP00000005665 | AGMAT isoform 1; Belongs to the arginase family. | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. | 0.922 |
| AGMAT | ALDH3A2 | ENSPPYP00000002136 | ENSPPYP00000023716 | AGMAT isoform 1; Belongs to the arginase family. | Aldehyde dehydrogenase family 3 member A2; Catalyzes the oxidation of medium and long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. | 0.922 |
| AGMAT | ALDH7A1 | ENSPPYP00000002136 | ENSPPYP00000023896 | AGMAT isoform 1; Belongs to the arginase family. | ALDH7A1 isoform 1; Belongs to the aldehyde dehydrogenase family. | 0.922 |
| AGMAT | ALDH9A1 | ENSPPYP00000002136 | ENSPPYP00000000664 | AGMAT isoform 1; Belongs to the arginase family. | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | 0.924 |
| AGMAT | CARNS1 | ENSPPYP00000002136 | ENSPPYP00000023856 | AGMAT isoform 1; Belongs to the arginase family. | CARNS1 isoform 6. | 0.907 |
| AGMAT | CNDP1 | ENSPPYP00000002136 | ENSPPYP00000010374 | AGMAT isoform 1; Belongs to the arginase family. | CNDP1 isoform 2. | 0.924 |
| AGMAT | CNDP2 | ENSPPYP00000002136 | ENSPPYP00000010372 | AGMAT isoform 1; Belongs to the arginase family. | Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis. | 0.924 |
| AGMAT | GATM | ENSPPYP00000002136 | ENSPPYP00000007301 | AGMAT isoform 1; Belongs to the arginase family. | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development (By similarity). | 0.924 |
| AGMAT | GLUL | ENSPPYP00000002136 | ENSPPYP00000000500 | AGMAT isoform 1; Belongs to the arginase family. | Glutamine synthetase. | 0.891 |
| ALDH1B1 | AGMAT | ENSPPYP00000021352 | ENSPPYP00000002136 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | AGMAT isoform 1; Belongs to the arginase family. | 0.923 |
| ALDH1B1 | ALDH2 | ENSPPYP00000021352 | ENSPPYP00000005665 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. | 0.978 |
| ALDH1B1 | ALDH3A2 | ENSPPYP00000021352 | ENSPPYP00000023716 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | Aldehyde dehydrogenase family 3 member A2; Catalyzes the oxidation of medium and long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. | 0.916 |
| ALDH1B1 | ALDH7A1 | ENSPPYP00000021352 | ENSPPYP00000023896 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | ALDH7A1 isoform 1; Belongs to the aldehyde dehydrogenase family. | 0.462 |
| ALDH1B1 | CARNS1 | ENSPPYP00000021352 | ENSPPYP00000023856 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | CARNS1 isoform 6. | 0.900 |
| ALDH1B1 | CNDP1 | ENSPPYP00000021352 | ENSPPYP00000010374 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | CNDP1 isoform 2. | 0.913 |
| ALDH1B1 | CNDP2 | ENSPPYP00000021352 | ENSPPYP00000010372 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis. | 0.913 |
| ALDH1B1 | GATM | ENSPPYP00000021352 | ENSPPYP00000007301 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | Glycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development (By similarity). | 0.909 |
| ALDH1B1 | GLUL | ENSPPYP00000021352 | ENSPPYP00000000500 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | Glutamine synthetase. | 0.827 |
| ALDH2 | AGMAT | ENSPPYP00000005665 | ENSPPYP00000002136 | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. | AGMAT isoform 1; Belongs to the arginase family. | 0.922 |