STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CELA2BCELA2B isoform 3; Belongs to the peptidase S1 family. (260 aa)    
Predicted Functional Partners:
CR201_G0045236
CELA2A isoform 2; Belongs to the peptidase S1 family.
  
 
 
0.993
CELA3B
CELA3A isoform 1; Belongs to the peptidase S1 family.
  
 
0.990
CPA1
Carboxypeptidase A1.
   
 
 0.779
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
 
 0.777
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.739
CPA2
CPA2 isoform 1.
   
 
 0.734
CTRC
CTRC isoform 1; Belongs to the peptidase S1 family.
   
    0.733
PPY
Pancreatic polypeptide.
   
    0.665
ENSPPYP00000007938
Transmembrane protease serine 8.
  
 
 0.639
KLK5
KLK5 isoform 1; Belongs to the peptidase S1 family.
  
 
0.629
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.