STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CELA2BCELA2B isoform 3; Belongs to the peptidase S1 family. (260 aa)    
Predicted Functional Partners:
CELA3B
CELA3A isoform 1; Belongs to the peptidase S1 family.
  
  
0.795
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
 
 0.734
CPA1
Carboxypeptidase A1.
   
 
 0.675
CPA2
CPA2 isoform 1.
   
 
 0.658
PPY
Pancreatic polypeptide.
   
    0.637
ENSPPYP00000020454
annotation not available
  
 
  0.579
ENSPPYP00000007938
Transmembrane protease serine 8.
  
 
  0.542
MST1R
MST1R isoform 1.
    
 0.517
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.505
KLK5
KLK5 isoform 1; Belongs to the peptidase S1 family.
  
 
 
0.501
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.