Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPPBNatriuretic peptide B. (134 aa)    
Predicted Functional Partners:
NPR3
NPR3 isoform 5.
    
 0.992
NPR1
Guanylate cyclase.
    
 0.985
NPR2
Guanylate cyclase.
    
 0.925
NPPA
Natriuretic peptide A.
   
  
 0.785
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.743
TNNI3
TNNI3 isoform 3.
   
  
 0.697
NPPC
Natriuretic peptide C.
      
 0.655
TNNT2
TNNT2 isoform 18.
   
  
 0.621
CR201_G0019319
CRP isoform 5.
      
 0.615
CYSLTR2
Cysteinyl leukotriene receptor 2.
      
 0.570
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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