EXOSC10 protein (Pongo abelii) - STRING interaction network

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Score

EXOSC10

EXOSC10 isoform 2. (905 aa)

Predicted Functional Partners:

EXOSC9

0.998

MPHOSPH6

0.997

EXOSC1

0.995

DIS3

0.995

EXOSC4

0.995

MTREX

0.994

EXOSC2

0.994

EXOSC5

0.993

C1D

0.993

EXOSC7

0.993

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1D	DIS3	ENSPPYP00000013776	ENSPPYP00000006166	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	0.930
C1D	EXOSC1	ENSPPYP00000013776	ENSPPYP00000002937	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	Exosome component 1.	0.981
C1D	EXOSC10	ENSPPYP00000013776	ENSPPYP00000002191	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	EXOSC10 isoform 2.	0.993
C1D	EXOSC2	ENSPPYP00000013776	ENSPPYP00000022078	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	EXOSC2 isoform 3.	0.979
C1D	EXOSC4	ENSPPYP00000013776	ENSPPYP00000021264	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	EXOSC4 isoform 1.	0.979
C1D	EXOSC5	ENSPPYP00000013776	ENSPPYP00000011211	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	EXOSC5 isoform 1.	0.980
C1D	EXOSC7	ENSPPYP00000013776	ENSPPYP00000015600	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	EXOSC7 isoform 6.	0.979
C1D	EXOSC9	ENSPPYP00000013776	ENSPPYP00000016797	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	Exosome component 9.	0.981
C1D	MPHOSPH6	ENSPPYP00000013776	ENSPPYP00000008567	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	M-phase phosphoprotein 6.	0.988
C1D	MTREX	ENSPPYP00000013776	ENSPPYP00000017285	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	SKIV2L2 isoform 1.	0.969
DIS3	C1D	ENSPPYP00000006166	ENSPPYP00000013776	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	Nuclear nucleic acid-binding protein C1D; Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi- subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). Belongs to the C1 [...]	0.930
DIS3	EXOSC1	ENSPPYP00000006166	ENSPPYP00000002937	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	Exosome component 1.	0.998
DIS3	EXOSC10	ENSPPYP00000006166	ENSPPYP00000002191	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	EXOSC10 isoform 2.	0.995
DIS3	EXOSC2	ENSPPYP00000006166	ENSPPYP00000022078	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	EXOSC2 isoform 3.	0.998
DIS3	EXOSC4	ENSPPYP00000006166	ENSPPYP00000021264	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	EXOSC4 isoform 1.	0.993
DIS3	EXOSC5	ENSPPYP00000006166	ENSPPYP00000011211	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	EXOSC5 isoform 1.	0.991
DIS3	EXOSC7	ENSPPYP00000006166	ENSPPYP00000015600	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	EXOSC7 isoform 6.	0.993
DIS3	EXOSC9	ENSPPYP00000006166	ENSPPYP00000016797	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	Exosome component 9.	0.996
DIS3	MPHOSPH6	ENSPPYP00000006166	ENSPPYP00000008567	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	M-phase phosphoprotein 6.	0.957
DIS3	MTREX	ENSPPYP00000006166	ENSPPYP00000017285	DIS3 isoform 1; Belongs to the RNR ribonuclease family.	SKIV2L2 isoform 1.	0.975