Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASZ1CASZ1 isoform 1. (1611 aa)    
Predicted Functional Partners:
ZFP1
Zinc finger protein 1 homolog; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.643
SH2B3
SH2B3 isoform 1.
      
 0.555
FEM1B
FEM1B isoform 1.
      
 0.479
RASGEF1C
RASGEF1C isoform 1.
      
 0.479
LYPD1
LYPD1 isoform 2.
      
 0.473
WDR92
WDR92 isoform 1.
      
 0.409
TP53INP1
Tumor protein p53 inducible nuclear protein 1.
      
 0.409
ISOC1
ISOC1 isoform 1.
      
 0.401
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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