STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAMP3Vesicle associated membrane protein 3. (100 aa)    
Predicted Functional Partners:
SNAP23
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 0.999
STX4
STX4 isoform 4; Belongs to the syntaxin family.
    
 0.999
STX1A
Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...]
    
 0.996
STX3
STX3 isoform 3; Belongs to the syntaxin family.
    
 0.994
VAMP2
VAMP2 isoform 2.
  
 
0.992
STX1B
STX1B isoform 1; Belongs to the syntaxin family.
    
 0.991
STX6
Syntaxin-6; Involved in intracellular vesicle trafficking.
    
 0.988
STX2
STX2 isoform 2; Belongs to the syntaxin family.
    
 0.988
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
   
 0.986
STX10
STX10 isoform 6; Belongs to the syntaxin family.
    
 0.985
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.