KLHL21 protein (Pongo abelii) - STRING interaction network

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Score

KLHL21

Kelch like family member 21. (597 aa)

Predicted Functional Partners:

CUL3

0.970

KLHL9

0.851

KLHL28

0.763

KLHL13

0.723

KLHL34

0.721

CUL1

0.671

COMMD9

0.642

COMMD5

0.642

SEC14L1

0.619

RBX1

0.616

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COMMD5	COMMD9	ENSPPYP00000021301	ENSPPYP00000003848	COMM domain containing 5.	COMM domain containing 9.	0.976
COMMD5	CUL1	ENSPPYP00000021301	ENSPPYP00000020352	COMM domain containing 5.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.454
COMMD5	CUL3	ENSPPYP00000021301	ENSPPYP00000014786	COMM domain containing 5.	CUL3 isoform 1; Belongs to the cullin family.	0.568
COMMD5	KLHL21	ENSPPYP00000021301	ENSPPYP00000002247	COMM domain containing 5.	Kelch like family member 21.	0.642
COMMD5	RBX1	ENSPPYP00000021301	ENSPPYP00000013235	COMM domain containing 5.	RBX1 isoform 1.	0.567
COMMD9	COMMD5	ENSPPYP00000003848	ENSPPYP00000021301	COMM domain containing 9.	COMM domain containing 5.	0.976
COMMD9	CUL3	ENSPPYP00000003848	ENSPPYP00000014786	COMM domain containing 9.	CUL3 isoform 1; Belongs to the cullin family.	0.555
COMMD9	KLHL21	ENSPPYP00000003848	ENSPPYP00000002247	COMM domain containing 9.	Kelch like family member 21.	0.642
COMMD9	RBX1	ENSPPYP00000003848	ENSPPYP00000013235	COMM domain containing 9.	RBX1 isoform 1.	0.586
CUL1	COMMD5	ENSPPYP00000020352	ENSPPYP00000021301	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	COMM domain containing 5.	0.454
CUL1	CUL3	ENSPPYP00000020352	ENSPPYP00000014786	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	CUL3 isoform 1; Belongs to the cullin family.	0.878
CUL1	KLHL21	ENSPPYP00000020352	ENSPPYP00000002247	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	Kelch like family member 21.	0.671
CUL1	KLHL28	ENSPPYP00000020352	ENSPPYP00000006563	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	Kelch like family member 28.	0.457
CUL1	RBX1	ENSPPYP00000020352	ENSPPYP00000013235	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	RBX1 isoform 1.	0.999
CUL3	COMMD5	ENSPPYP00000014786	ENSPPYP00000021301	CUL3 isoform 1; Belongs to the cullin family.	COMM domain containing 5.	0.568
CUL3	COMMD9	ENSPPYP00000014786	ENSPPYP00000003848	CUL3 isoform 1; Belongs to the cullin family.	COMM domain containing 9.	0.555
CUL3	CUL1	ENSPPYP00000014786	ENSPPYP00000020352	CUL3 isoform 1; Belongs to the cullin family.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.878
CUL3	KLHL13	ENSPPYP00000014786	ENSPPYP00000023125	CUL3 isoform 1; Belongs to the cullin family.	KLHL13 isoform 9.	0.981
CUL3	KLHL21	ENSPPYP00000014786	ENSPPYP00000002247	CUL3 isoform 1; Belongs to the cullin family.	Kelch like family member 21.	0.970
CUL3	KLHL28	ENSPPYP00000014786	ENSPPYP00000006563	CUL3 isoform 1; Belongs to the cullin family.	Kelch like family member 28.	0.800